Skip Navigation

Technology Development

Office of Research

Office of Research

PRRS Matrix Envelope Protein Monoclonal Antibodies

Disclosure #: 1050
Description: A recently developed hybridoma that produces monoclonal antibodies to a protein in the virus causing porcine reproductive and respiratory syndrome (PRRS) may have value to researchers and companies working in this area. PRRS is an economically important disease, causing annual losses of around $600 million in the swine industry. Although vaccines have been developed to help prevent the spread of PRRS, reagents such as monoclonal antibodies will be valuable tools to scientists developing newer, more efficacious immunizations.
Advantage(s):
  • Only known monoclonal antibody for M antigen of PRRSV II (US type)
  • Directed to a highly conserved sequential epitope in M endodomain
  • Highly effective to characterize PRRSV M protein by indirect immunofluorescence, immunoprecipitation or Western Blot
Application(s): Detection and quantification of PRRSV for:
  • Academic research
  • Vaccine development
  • Quality control of subunit vaccines
  • Diagnostics
Publication(s): de Lima M., Pattnaik A.K., Flores E.F., Osorio F.A. Serologic marker candidates identified among B-cell linear epitopes of Nsp2 and structural proteins of a North American strain of porcine reproductive and respiratory syndrome virus(2006) Virology, 353 (2), pp. 410-421.
Licensing Manager: Dr. Nicholas Aliano
naliano@nutechventures.org
(402) 472-3680
Inventor(s): Dr. Fernando Osorio
Technology Brief: 1050 Marketing Brief - Osorio - PRRS Virus Antibodies.pdf


Back